Melchor Rodrigo
Dr Melchor Rodrigo, MD, Professor of Neurology, Buenos Aires, Argentina
Title: The underdiagnosis of cryoglobulinemias, a potentially big problem at the long term
Biography
Biography: Melchor Rodrigo
Abstract
To evaluate the prevalence of cryoglobulinemias, as well as it,s commorbidities and ethiology.Autoimmune diseases could very well be referred to as a spectrum too, being that in most cases you find some form of other autoinmune disease overlapped. But what about cryoglobulinemia? Could this disease go very much undiagnosed, despite suspecting an autoinmune disorder? Cryoglobulins are immunoglobulins that precipitate at temperaturas below 37ºC. They Usually redissolve Upon rewarming.Clinically, it usually presents with púrpura (a purplish discoloration from bleeding under the skin.) It also usually presents with severe joint pain and muscle pain (something known as Metzler´s Triad).The problem is that sometimes these immuneglobulins attach together and form immunecomplexes, which compromise blod flow and can hurt certain organs such as the kidneys and the liver.